one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the procedure of numerous myeloma. Its synthesis or research is crucial for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets unique different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the production approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked to its creation.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of CAS NO. 314771-76-1 paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment method of colorectal most cancers and small mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-9): This compound is associated with the synthesis of adamantane derivatives, that have different applications, which include antiviral Qualities.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for sort two diabetic issues that inhibits CAS NO. 302964-24-5 the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which can be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication applied to deal with style two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).